医学
类风湿性关节炎
免疫学
发病机制
BCL6公司
T细胞
CD154
疾病
关节炎
趋化因子
自身免疫性疾病
炎症
B细胞
抗体
免疫系统
生发中心
细胞毒性T细胞
CD40
内科学
生物
遗传学
体外
作者
Masaru Takeshita,Katsuya Suzuki,Yasushi Kondo,Rimpei Morita,Yuumi Okuzono,Keiko Koga,Yoshiaki Kassai,Kanae Gamo,Maiko Takiguchi,Rina Kurisu,Hideyuki Mototani,Yukihiko Ebisuno,Akihiko Yoshimura,Tsutomu Takeuchi
标识
DOI:10.1136/annrheumdis-2018-214885
摘要
Our multi-dimensional investigation identified disease relevant T-cell subsets and gene signatures deeply involved in pathogenesis of RA. These findings could aid in our understanding of essential roles of T cells in RA and will facilitate to development better diagnostic and therapeutic interventions.
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