Objective To investigate the effects of Pereutaneous Nephrolithotomy in complexity kidney stones.Methods 40 patients of complexity kidney stones,the guidance by B ultrasound,all these cases are applied Pereutaneous nePhrolithotomy.Results 40 patients one-time stone-free are 32 cases,8 cases in the other are 2 times stone-free successful,The average operation time is 80~150 minutes.Postoperative review,the stone-free rate is 80%(32cases),8 cases of residual.Conclusion It is valuable about pereutaneous nePhrolithotomy in complexity kidney stones,the advantage of small trauma,definite effect,little bleeding and rapid recovery.Suggest further promotion in clinical.