The reverse osmosis membrane is applied widely in pure water production process due to its excellent performance of steady production,low operation cost,non-pollution to environment et cetera.The reverse osmosis membrane may be polluted itself by suspended particles and indissoluble matters in normal operation,and this will lower the performance of reverse osmosis membrane,therefore cleaning membrane is very important.By analyzing the membrane pollution of reverse osmosis system in Shiliquan Power Plant of Huadian International Corporation Limited,a set of feasible membrane cleaning technology,including the prescription and process,was developed,which may offer the same pure water production process as a reference.