Study Progress of Anti-apoptosis Protein Bfl-1/hA1

Bcl-2 family proteins are the key regulators of cell apoptosis.Bfl-1/hA1 has been well studied among anti-apoptosis protein family members although as a later member in Bcl-2 family.It plays an important role in the up-stream activation and down-stream effect of cell anti-apoptosis mechanism by its special domain structure.It also exerts great impacts on the development of apoptosis related diseases,such as inflammation and hematological cancer.Anti-apoptosis protein Bfl-1/hA1 may be a new therapeutic target of apoptosis-related diseases.