Catalyst-free and multicomponent synthesis of 3-aminoalkylated indolesviaa Mannich-type reaction: multitargeted anticancer, tyrosinase and α-glucosidase inhibitory activities

3-Aminoalkylated indoles, synthesized via a multicomponent Mannich-like reaction, are evaluated for enzyme inhibition; 5e and 5f are shown to be prospective multitargeted anticancer agents, and the cytotoxic mechanism of action is demonstrated via molecular docking study.