Landscape of germline and somatic alterations of HRR and MMR genes in 328 Chinese patients with primary epithelial ovarian cancer(EOC)

Objective: Alterations of homologous recombination (HRR) and mismatch repair (MMR) pathways in epithelial ovarian cancer (EOC) have both hereditary and therapeutic implications. The aim of this study was to explore the germline and somatic landscape of genetic variations of HRR and MMR genes simultaneously in Chinese EOC patients.