Copper-Catalyzed Tandem Nucleophilic Ring-Opening/Intramolecular Oxidative Amidation of N -Tosylaziridines and Hydrazones under Aerobic Conditions

A novel and efficient copper-catalyzed tandem reaction of N-tosylaziridines and hydrazones under aerobic conditions to afford the functionalized tetrahydrotriazines is described. The process involves a nucleophilic ring-opening and an intramolecular oxidative amidation.