癌症研究
肿瘤微环境
免疫系统
胰腺癌
癌变
肿瘤进展
生物
免疫疗法
胰腺肿瘤
癌症
化学
免疫学
肿瘤细胞
遗传学
作者
Cheng‐Cao Sun,Youqiong Ye,Zhi Tan,Yuan Liu,Yajuan Li,Wei Hu,Ke Liang,Sergey D. Egranov,Lisa A. Huang,Zhao Zhang,Yaohua Zhang,Jun Yao,Tina K. Nguyen,Zilong Zhao,Andrew Wu,Jeffrey R. Marks,Abigail S. Caudle,Ayşegül A. Şahin,Jianjun Gao,Seth T. Gammon
出处
期刊：Science Advances
[American Association for the Advancement of Science]
日期：2023-02-01
卷期号：9 (5): eadd6995-eadd6995
被引量：55
标识
DOI：10.1126/sciadv.add6995
摘要
suppressed PDAC tumor growth. Furthermore, depletion of TASc using a small-molecule inhibitor effectively sensitized PDAC to immunotherapy, signifying the important roles of TASc in PDAC immune resistance.
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