金黄色葡萄球菌
真菌
立体化学
抗菌活性
倍半萜
萜类
二维核磁共振波谱
曲霉
发酵
十一烷
化学
生物
微生物学
植物
细菌
有机化学
遗传学
作者
Siwen Niu,Shuhuan Huang,Juan Wang,Jianlin He,Meixiang Chen,Gaiyun Zhang,Bihong Hong
标识
DOI:10.1080/14786419.2022.2144299
摘要
The chemical examination of the rice solid fermentation products of the deep-sea-derived fungus Aspergillus puniceus A2 resulted in the isolation of one new sesquiterpenoid malfilanol C (1), together with a rare analogue malfilanol B (2). The planar structure of 1 was resolved on the basis of the extensive analyses of the spectroscopic data (HRESIMS and NMR spectra), and its absolute configuration was assigned by quantum chemical calculation of the ECD data. Compound 1, featuring a bicyclo[5.4.0]-undecane nucleus skeleton, was the third example of this subclass sesquiterpenoids found from nature. Additionally, the subclass sesquiterpenoids 1 and 2 were discovered from marine-derived-fungi for the first time. All the isolated metabolites were evaluated the antibacterial activities against Staphylococcus aureus ATCC 29213 and Escherichia coli ATCC 25922. Compound 1 exhibited weak antibacterial activity against S. aureus ATCC 29213.
科研通智能强力驱动
Strongly Powered by AbleSci AI