The impact of depression and anxiety on the risk of exacerbation in adults with bronchiectasis: a prospective cohort study

Exacerbations significantly contribute to impaired quality of life (QoL), accelerated lung function decline and premature mortality in bronchiectasis [1]. Prevention of exacerbations is one of the key goals in international guidelines for bronchiectasis [2, 3]. Thus, identifying risk factors associated with exacerbation will be important to design and deliver the right interventions to the right people, and are an active area of research [4]. Depression was associated with an increased risk of exacerbations in patients with bronchiectasis and may be a crucial “treatable trait” for exacerbation prevention