Small Dense Low-Density Lipoprotein Cholesterol and Renal Function: A Missing Link in Cardiovascular Risk Assessment for Chronic Kidney Disease Patients

and kidney function.Given that CKD constitutes a major risk factor for IHD, 4 exploring the relationship between sdLDL-C, renal function, and cardiovascular outcomes is essential.The finding that L-LDL-C/H-sdLDL-C patients exhibited similar IHD risk as H-LDL-C/H-sdLDL-C patients suggests that lipid management in CKD should target both total LDL-C and LDL quality.We commend the authors and anticipate future research will elucidate clinical significance of sdLDL-C in CKD.