医学
β肾上腺素能受体激酶
内科学
心力衰竭
淋巴细胞
G蛋白偶联受体激酶
内分泌学
受体
BETA（编程语言）
肾上腺素能受体
心脏病学
G蛋白
计算机科学
G蛋白偶联受体
程序设计语言
作者
Guido Iaccarino,Emanuele Barbato,Ersilia Cipolletta,Vincenzo De Amicis,Kenneth B. Margulies,Dario Leosco,Bruno Trimarco,Walter J. Koch
标识
DOI：10.1093/eurheartj/ehi429
摘要
Myocardial GRK2 expression and activity are mirrored by lymphocyte levels of this kinase, and its elevation in HF is associated with the loss of beta-AR responsiveness and appears to increase with disease severity. Therefore, lymphocytes may provide a surrogate for monitoring cardiac GRK2 in human HF.
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