清脆的
基因敲除
RNA干扰
Cas9
前列腺癌
基因
CRISPR干扰
核糖核酸
癌症
癌症研究
基因组编辑
基因表达
计算生物学
化学
生物
遗传学
作者
Arpita Poddar,Suneela Pyreddy,Francesco Carraro,Sudip Dhakal,Andrea Rassell,Matthew R. Field,T. Srinivasa Reddy,Paolo Falcaro,Cara M. Doherty,Ravi Shukla
摘要
Metal–organic-frameworks for gene therapy in prostate cancer – ZIF-C based delivery of RNA interference and CRISPR/Cas9 causes host gene expression knockdown. Coating with a green tea phytochemical enhances uptake and increases cancer cytotoxicity.
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