材料科学
挤压
多孔性
聚乙二醇
复合数
塑料挤出
复合材料
蛋白质丝
聚乳酸
热塑性塑料
3D打印
制作
化学工程
聚合物
工程类
替代医学
病理
医学
作者
Cristina Pascual-González,C. Thompson,Jimena de la Vega,Nicolás Biurrun Churruca,Juan P. Fernandéz‐Blázquez,I. Lizarralde,D. Herráez-Molinero,Carlos González,Javier LLorca
标识
DOI:10.1108/rpj-06-2021-0152
摘要
Purpose This paper aims to develop a novel strategy to manufacture poly-lactic acid (PLA) filaments reinforced with Mg particles for fused filament fabrication of porous scaffolds for biomedical applications. Design/methodology/approach The mixture of PLA pellets and Mg particles was extruded twice, the second time using a precision extruder that produces a filament with zero porosity, constant diameter and homogeneous dispersion of Mg particles. The physico-chemical properties of the extruded filaments were carefully analysed to determine the influence of Mg particles on the depolymerisation of PLA during high temperature extrusion and the optimum melt flow index to ensure printability. Findings It was found that the addition of a polyethylene glycol (PEG) plasticizer was necessary to allow printing when the weight fraction of Mg was above 4%. It was possible to print porous face-centre cubic scaffolds with good geometrical accuracy and minimum porosity with composite filaments containing PEG. Originality/value The new strategy is easily scalable and seems to be very promising to manufacture biodegradable thermoplastic/metal composite filaments for 3D printing that can take advantage of the different properties of both components from the viewpoint of tissue engineering.
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