医学
疤痕
皮肤病科
病因学
遗传倾向
病理生理学
病理
疾病
作者
Mimi R. Borrelli,Michelle Griffin,Ledibabari M. Ngaage,Michael T. Longaker,H. Peter Lorenz
标识
DOI:10.1097/prs.0000000000008065
摘要
Summary: Striae distensae, or stretch marks, are common linear lesions of atrophic skin characterized histologically by epidermal atrophy, absent rete ridges, and alterations in connective tissue architecture. Hormonal excess, mechanical stress, and genetic predisposition are all associated with striae distensae, but their exact pathogenesis remains unknown. Despite a multitude of options, no single treatment has yet proven effective. In this article, the authors describe an up-to-date overview of striae distensae in terms of their etiology, pathophysiology, and therapeutic options. Further research is required to better elucidate their pathophysiology and to develop targeted effective treatments.
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