不确定
医学
甲状腺结节
细针穿刺
甲状腺
危险分层
活检
病理
细胞学
针吸细胞学
内科学
数学
纯数学
作者
Michiya Nishino,Jeffrey F. Krane
出处
期刊:Acta Cytologica
[S. Karger AG]
日期:2019-04-04
卷期号:64 (1-2): 40-51
被引量:28
摘要
Ancillary molecular testing has emerged as a promising way to refine the preoperative risk stratification of thyroid nodules with indeterminate fine needle aspiration (FNA) biopsy results. Commercially available molecular tests for thyroid FNAs include those that analyze samples for mutations and gene fusions, gene expression alterations, microRNA expression alterations, chromosomal copy number alterations, or a combination thereof. This review summarizes the performance characteristics of the most current iterations of three tests currently marketed for cytologically indeterminate thyroid nodules: ThyroSeq v3, ThyGeNEXT/ThyraMIR, and Afirma Gene Sequencing Classifier.
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