聚乙烯醇
碘
化学
乙醇
抗菌剂
酒
色谱法
核化学
食品科学
生物化学
有机化学
作者
Hiroshi Hatano,Masako Sakamoto,Kazuo Hayashi,Seigo Kamiya
出处
期刊:Japanese Journal of Ophthalmology
日期:2015-08-01
卷期号:119 (8): 503-10
被引量:2
摘要
Temperature, concentration and time are the three factors that affect the inactivation capacity of iodine antiseptics. We investigated the effect of these factors on the microbe inactivation of Iodine-Polyvinyl Alcohol ophthalmic and eye washing solution (PA * IODO), and also investigated the preservation conditions on stability of the inactivation activity of the PA * IODO.Test microbes were mixed with PA * IODO, varying the three factors. The live microbes were counted after each reaction. The effects of plugging and preservation temperature were investigated to determine the preserving stability.The inactivation capacity of PA * IODO tended to decrease in almost all microbes tested at 4 degrees C. Twenty times or less diluted PA * IODO killed almost all microbes completely. The time effect was more marked in viruses. Plugging and low-temperature made iodine concentration in diluted PA * IODO remain relatively high.The concentration of PA * IODO affected the inactivation ability more than the temperature and time, although all the three factors correlated positively to the inactivation. For preservation the diluted PA * IODO needed plugging and low temperature.
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