高尿酸血症
益生菌
尿酸
医学
黄嘌呤氧化酶
免疫系统
脾脏
拉伤
痛风
免疫学
生物
药理学
黄嘌呤氧化酶抑制剂
酶
微生物学
肝功能
酶分析
作者
Yongtao Xie,L E Li,T M Zou,Haifeng Ye,Jinzhong Tian
出处
期刊:PubMed
[National Institutes of Health]
日期:2026-05-25
卷期号:42 (5): 2261-2273
标识
DOI:10.13345/j.cjb.250926
摘要
D801 significantly attenuated hyperuricemia in mice, reducing the serum uric acid level by 20.65%. Moreover, the strain decreased the xanthine oxidase (XOD) activity by 36.24% and 13.54% in the mouse liver and serum, respectively. Importantly, it reduced the spleen index by 17.09%. The results suggest that strain D801 improves the immune function and alleviates systemic inflammation. The core significance of this study lies in offering a safer approach for hyperuricemia.
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