Synthesis of Quinoxaline-Based Compounds and Their Antitumor and Antiviral Potentials

Background: Quinoxaline-based derivatives present a group of very important heterocyclic pharmacophores which occupied the attention of a large number of scientists in the last few decades. Compounds with quinoxaline fragment have significant antitumor and antiviral potential, proved by an in vitro or/and in vivo study, and possess therapeutic potential. Conclusion: In this review article, we present an overview of the developments in the area of synthesis of compounds that contain quinoxaline scaffold with antitumor or antiviral activities. Keywords: o-Phenylenediamine, Diketo acid, quinoxaline, antitumor activity, antiviral activity, benzodiazepene.