Adsorption of antidepressant and cardiovascular drugs to activated charcoal: amitriptyline, bupropion, minoxidil, propranolol, and venlafaxine

This study supports the use of activated charcoal for gastrointestinal decontamination in overdoses involving amitriptyline, bupropion, minoxidil, propranolol, and venlafaxine. However, drug-specific differences in adsorption behavior suggest a need for refined dosing strategies, particularly in cases involving drugs with lower binding efficiencies.