Engineered Nanomaterials to Potentiate CRISPR/Cas9 Gene Editing for Cancer Therapy (Adv. Mater. 13/2024)

Nanomaterials-Mediated Gene Editing for Cancer Therapy In article number 2300665, Yu Tao, Mingqiang Li, Jianxun Ding, and co-workers present a comprehensive overview of the revolutionary potential of applying nanomaterial-enhanced CRISPR/Cas9 gene editing systems for cancer therapy. The rationally engineered nanoformulations exhibit a pronounced enhancement of the safety, efficiency, and specificity of gene editing events, increasing accessibility of CRISPR/Cas9 toolkits to disrupt the tumor-associated genes and resulting in effective tumor eradication.