Transmission characteristics of Sudan virus disease outbreak in Uganda in early 2025

In early 2025, Sudan virus (SUDV) caused an self-limited outbreak in Uganda including a total of 14 cases. We preliminarily assessed the transmission characteristics of Sudan virus disease, estimating mean serial interval of 13.7 days (95% CrI: 12.2, 15.8), and secondary attack rate of 17.8%, and we found a high transmission heterogeneity with 6.1% (95% CrI: 3.3, 12.5) of cases generated 80% of all transmission events. Timely and continuous monitoring of SUDV circulation, and real-time risk assessment were required at the local community level.