Supersaturation Behavior: Investigation of Polymers Impact on NucleationKinetic Profile for Rationalizing the Polymeric Precipitation Inhibitors

The HPMC K15M and xanthan Gum showed the best crystallization inhibitor effect for the maintenance of superfluity conditions till the drug absorption time. The xanthan gum is based on the "glider" concept, and this shows the novelty of this preliminary research. The screening methodology used for rationalizing the best polymers used in the superfluity formulations development successfully.