风险评估
中国
代理(哲学)
食品安全
工作(物理)
风险分析(工程)
工程类
业务
环境规划
政治学
医学
计算机科学
地理
机械工程
哲学
计算机安全
认识论
病理
法学
作者
Di Yang,Hui Yang,Miaoying Shi,Xudong Jia,Haixia Sui,Zhaoping Liu,Yongning Wu
标识
DOI:10.3389/ftox.2023.1292373
摘要
Novel techniques and methodologies are being developed to advance food safety risk assessment into the next-generation. Considering the shortcomings of traditional animal testing, new approach methodologies (NAMs) will be the main tools for the next-generation risk assessment (NGRA), using non-animal methodologies such as in vitro and in silico approaches. The United States Environmental Protection Agency and the European Food Safety Authority have established work plans to encourage the development and application of NAMs in NGRA. Currently, NAMs are more commonly used in research than in regulatory risk assessment. China is also developing NAMs for NGRA but without a comprehensive review of the current work. This review summarizes major NAM-related research articles from China and highlights the China National Center for Food Safety Risk Assessment (CFSA) as the primary institution leading the implementation of NAMs in NGRA in China. The projects of CFSA on NAMs such as the Food Toxicology Program and the strategies for implementing NAMs in NGRA are outlined. Key issues and recommendations, such as discipline development and team building, are also presented to promote NAMs development in China and worldwide.
科研通智能强力驱动
Strongly Powered by AbleSci AI