Comparison of endovascular versus open repair of abdominal aortic aneurysms:a randomized trial

Objective:To compare postoperative outcomes up to 6 months after endovascular or open repair of AAA.Methods:A randomized,single center clinical trial of 100 patients with eligible AAA who were candidates for both elective endovascular repair and open repair of AAA.Patients were randomized to receive either EVAR(endovascular aneurysm repair) or OR(open repair) of AAA.All-cause deaths,systemic and surgery-related complication were documented.Intraoperative data was also collected.All patients were followed up to 6 months after surgery.Statistical analysis was applied to process collected data.Results:Fifty patients were assigned to EVAR group and 50 to OR group.Thirty-nine patients underwent OR and 61 underwent EVAR eventually.Perioperative mortality was zero for both groups.When followed up to 6 months,all-cause mortality was lower for EVAR(0 % vs.2.6%),but there was no significant difference between the 2 groups.Patients in the EVAR group had reduced median procedure time,blood loss,transfusion requirement,hospital stay,but required much more expensive cost(P0.05).There were no significant differences between the 2 groups in major systemic complication,surgery related complication,secondary therapeutic procedures,but EVAR showed a better outcome during perioperative period.Conclusion:In this report of short-term outcomes after elective AAA repair,perioperative mortality and mobility was low for both procedures.Both EVAR and OR are safe and effective options for AAA.Longer-term outcome data are needed to fully assess the relative merits of the 2 procedures.