Chemical Constituents from Cibotium barometz and their Scavenging Activities for DPPH Radical

Objective:Study on the chemical constituents from Cibotium barometz and their scavenging activities for 2,2-diphenyl-2-picrylhydrazyl(DPPH) radical.Method: The chemical constituent from70% alcohol extract of C.barometz was isolated on chromatograph of silica gel and sephadex LH-20 and HPLC,their structure were elucidated on the basis of spectra data and the compounds were tested for their scavenging activities on DPPH radical.Result: Ten compounds were purified and their structure were identified as 1-O-caffeyl-D-glucopyranose(1),6-O-caffeyl-D-glucopyranose(2),3-O-caffeyl-D-glucopyranose(3),3-hydroxymethyl-2(5H)-furanone(4),β-miroside(5),cibotiumbaroside A(6),protocatechuic acid(7),glucose(8),mannose(9),Corchoionoside C(10),kojic acid(11).Three isolated compounds showed strong scavenging activities on DPPH radical.Conclusion: Compound 1-5 were isolated for the first time from C.barometz.among of them,compound 1,compound 3 and compound 6 showed significant antioxidant activity,and the scavenging activity of compound 1 was similar to that of Vit C.