神经嵴
神经管
神经褶
神经板
神经形成
原肠化
神经上皮细胞
生物
神经科学
人口
脊椎动物
解剖
细胞生物学
胚胎
神经干细胞
干细胞
胚胎发生
遗传学
基因
医学
环境卫生
作者
Chang Jun Bae,Jean Pierre Saint-Jeannet
出处
期刊:Elsevier eBooks
[Elsevier]
日期:2014-01-01
卷期号:: 27-49
被引量:11
标识
DOI:10.1016/b978-0-12-401730-6.00002-8
摘要
The neural crest is a multipotent population of migratory cells unique to the vertebrate embryo. Neural crest cells form at the neural plate border during gastrulation and, around the time of neural tube closure, leave the neuroepithelium to produce a diverse array of cell types, contributing to multiple organ systems. Neural crest cells are generated through a sequence of events orchestrated by the modulation of several signaling pathways and the activation of a complex network of transcription factors. Here, we review recent advances in the characterization of the molecular players directing neural crest induction and specification, comparing data from different model organisms.
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