Fast digitally reconstructed radiograph generation using particle-based statistical shape and intensity model

Statistical shape and intensity models (SSIMs) and digitally reconstructed radiographs (DRRs) were introduced for non-rigid 2D-3D registration and skeletal geometry/density reconstruction studies. The computation of DRRs takes most of the time during registration or reconstruction. The goal of this study is to propose a particle-based method for composing an SSIM and a DRR image generation scheme and analyze the quality of the images compared with previous DRR generation methods.