泽吉伯
昼夜节律
岩石2
内科学
内分泌学
生物钟
肌球蛋白轻链激酶
生物
收缩性
时钟
Rho相关蛋白激酶
医学
肌球蛋白
细胞生物学
磷酸化
作者
Toshiro Saito,Mayumi Hirano,Tomomi Ide,Toshihiro Ichiki,Noriyuki Koibuchi,Kenji Sunagawa,Katsuya Hirano
出处
期刊:Circulation
[Lippincott Williams & Wilkins]
日期:2012-11-23
卷期号:127 (1): 104-114
被引量:39
标识
DOI:10.1161/circulationaha.112.135608
摘要
ROCK2 plays a pivotal role in generating the intrinsic circadian rhythm of vascular contractility by receiving a cue from RORα. The ROCK2-mediated intrinsic rhythm of vascular contractility may underlie the diurnal variation of the incidence of cardiovascular diseases.
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