Influence of Individualized Stabilization on the Consistency of Supraclavicular Fossa Positioning in Breast Radiation Therapy: A Retrospective Study

The accurate stabilization of breast patients who are also undergoing supraclavicular fossa treatment is essential and can be challenging. Discrepancy in setup error for these patients often lies with the position of the clavicle in relationship with other anatomic structures. This study was performed to assess how individualized stabilization can improve patient's stability and reproducibility.Thirty patients stabilized with an individualized vacfix located on a Civco wing board (Civco Medical Solutions, Kalona, IA) were compared with 30 patients stabilized in the traditional manner on a Civco breast board (Civco Medical Solutions). Each of these patients underwent daily imaging using the Varian Clinac iX On-board Imaging System (Varian Medical Systems, Palo Alto, CA), and image mismatch data for each session were collected. Additionally, the relationship between the clavicle and vertebrae was assessed for each stabilization solution on a daily basis. Statistical analysis of this data was then performed using a mixed effects approach to take account of data grouping by patient specifically for the displacement error in each direction.The use of an individualized vacfix decreased the overall systematic and random setup errors and displayed a reduction in the standard deviation of setup error. Patients positioned using breast board stabilization with the clavicle as the match method were exposed in the longitudinal direction to a systematic error of a 95% confidence interval (CI) of 2.6-4.5 mm and a random error of a 95% CI of 2.7-3.2 mm. This was significantly reduced for vacfix stabilization with a systematic error of a 95% CI of 1.2-2.3 mm and a random error of a 95% CI of 1.8-2.3 mm. These data amount to a reduction of the systematic error by 40% (P = .02) and a random error by 25% (P = .003) when using the vacfix method compared with the breast board. The data displaying the relationship between the clavicle and other anatomy within the treatment volume appear to be more consistent with the individualized vacfix approach.Reproducible and consistent stabilization for the breast/supraclavicular fossa technique is vital in terms of ensuring accurate patient position. Analysis of the setup error for clavicle and spinous process matching strongly indicates a reduction in both the systematic and random setup error achieved by the vacfix. This illustrates the increased stability and reproducibility of patient positioning when an individualized vacfix is used.