PTEN公司
张力素
癌症研究
蛋白激酶B
PI3K/AKT/mTOR通路
基因敲除
磷酸酶
生物
磷酸戊糖途径
磷酸化
信号转导
细胞生物学
糖酵解
生物化学
细胞凋亡
酶
作者
Xuehui Hong,Ruipeng Song,Huiwen Song,Tongsen Zheng,Jiabei Wang,Yingjian Liang,Shuyi Qi,Zhao‐Yang Lu,Xuan Song,Hongchi Jiang,Lianxin Liu,Zhiyong Zhang
出处
期刊:Gut
[BMJ]
日期:2013-12-18
卷期号:63 (10): 1635-1647
被引量:138
标识
DOI:10.1136/gutjnl-2013-305302
摘要
These results establish the counteraction between PTEN and Tcl1 as a key mechanism that regulates the PPP and suggest that targeting the PTEN/Tcl1/hnRNPK/G6PD axis could open up possibilities for therapeutic intervention and improve the prognosis of patients with HCC.
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