Discovery and synthesis of (+)/(–)-muyoquinone A, a pair of rare cyclopropane bridge-containing pentacyclic benzoquinone dimers with cytotoxic activity

This work reports the structures, total synthesis via the Diels–Alder cascade reaction and cytotoxic activity of (±)-muyoquinone A, a pair of rare pentacyclic benzoquinone dimers isolated from the endophytic fungus Muyocopron laterale .