Objective To compare the appraisal values in different scoring for the prognosis of patients with severe trauma. Methods A total of 400 cases of patients with severe trauma from September 2012 to September2013 in the Affiliated Hospital of Hainan Medical University were graded by acute physiology and chronic health evaluation(APACHEⅡ), modified early warning score(MEWS) and simple clinical scoring(SCS). And then the effects of evaluation in three kinds of scoring systems for the prognosis of patients were compared. Results With the case fatality rate increasing, the scores of three kinds of scoring system were also increased as well. APACHEⅡ showed the minimal error value(0.026), while MEWS showed the maximal error value(0.034). The area under ROC curve of APACHE Ⅱ was maximal(0.866), while the area under ROC curve of MEWS was least(0.749). Conclusion All these three score systems can effectively predict the outcomes of patients with severe trauma, and the assessing accuracy is highest in APACHEⅡ and lowest in MEWS. SCS scoring system is accurate and easy and fast to be used, which is more conducive to early prognosis for patients with severe trauma.