Objective To observe the clinical effects of Long Bi Shu combined with behavior therapy for premature ejaculation(PE). Methods A total of 120 patients with PE were randomly divided into three groups:group A in which 40 cases were treated with Long Bi Shu and behavior therapy,group B in which 40 cases were treated with Long Bi Shu alone,and group C in which 40 cases were treated with behavior therapy alone. Intravaginal ejaculation latency time(IELT) and Chinese index of sexual function for premature ejaculation(CIPE) were observed before and after treatment. Results After treatment,the IELTs and CIPEs increased significantly(P0.01) in all groups,and they increased more significantly in group A than in groups B and C(P0.05); the total effective rate was higher in group A than in groups B and C(P0.05). Conclusion Long Bi Shu combined with behavior therapy is quite effective for premature ejaculation.