神经肽
医学
伤口愈合
糖尿病
炎症
糖尿病神经病变
神经科学
内科学
内分泌学
外科
生物
受体
作者
Georgios Theocharidis,Aristidis Veves
标识
DOI:10.1016/j.autneu.2019.102610
摘要
A C T Lower extremity ulcerations represent a major complication in diabetes mellitus and involve multiple physiological factors that lead to impairment of wound healing.Neuropeptides are neuromodulators implicated in various processes including diabetic wound healing.Diabetes causes autonomic and small sensory nerve fibers neuropathy as well as inflammatory dysregulation, which manifest with decreased neuropeptide expression and a disproportion in pro-and anti-inflammatory cytokine response.Therefore to fully understand the contribution of autonomic nerve dysfunction in diabetic wound healing it is crucial to explore the implication of neuropeptides.Here, we will discuss recent studies elucidating the role of specific neuropeptides in wound healing.
科研通智能强力驱动
Strongly Powered by AbleSci AI