医学
糖尿病性视网膜病变
生物标志物
眼科
淋巴细胞
内科学
逻辑回归
闭塞
白细胞
胃肠病学
糖尿病
生物化学
内分泌学
化学
作者
Aiping Zhang,Ning Li,J.-Y. Han,Yi Ma,Yingbo Ma,Wenjun Cao,Xinghuai Sun,Shengjie Li
标识
DOI:10.1080/09273948.2019.1677916
摘要
Purpose: To evaluate blood count–derived inflammation indexes as a detection or predictive marker for neovascular glaucoma (NVG) secondary to retinal vein occlusion (RVO) and diabetic retinopathy (DR).Methods: This was a retrospective, case-control study design. The level of white blood cell (WBC), neutrophil (N), neutrophil/lymphocyte ratio (NLR), and lymphocyte/monocyte ratio (LMR) were evaluated in NVG patients secondary to RVO or DR.Results: A significant difference was found in those biomarkers between control group and NVG secondary to RVO or DR. Logistic regression analysis revealed these indexes were associated with the risk of NVG in DR and RVO patients. Multiple linear regression analysis showed a significant correlation between NLR and visual fields mean deviation in the NVG-RVO group.Conclusions: This study indicated that WBC, N, NLR, and LMR were related to NVG, and NLR may be useful as an potential inflammation biomarker indicating the risk and severity for NVG secondary to RVO.
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