A General Simple Methodology for Synthesis of Isonitriles Using Benzene- 1,3-disulfonyl Dichloride

Isonitrile derivatives have been synthesized in good to high yields by dehydration of aliphatic and aromatic formamides in the presence of benzene-1,3-disulfonyl dichloride as easy and efficient reagent. Keywords: Benzene-1, 3-disulfonylchloride (BDS), isonitrile, multicomponent reactions (MCRs), triethylamine (TEA), Isocyanide-based, isonitriles, anion, formamides, temperature, BDD