‘Against all odds’, as this paper uses the term, confronts the fact that people at work often face situations challenging their professional values and orientation. They must decide whether to stick to their ethical principles or set them aside in the interest of a prevailing system that otherwise stacks the odds against them. The odds people in their professions may face result from limits, boundaries, obstacles or emerging risks. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.