磷酸果糖激酶
脱氢酶
柠檬酸合酶
酶
振膜(声学)
高压氧
内科学
氧化酶
琥珀酸脱氢酶
乳酸脱氢酶
内分泌学
充氧
磷酸戊糖途径
糖酵解
医学
生物
新陈代谢
生物化学
麻醉
高压氧
物理
扬声器
声学
作者
Nelson Ag,E Wolf,Hearon Cm,Li B
出处
期刊:PubMed
日期:1994-06-01
卷期号:21 (2): 193-8
摘要
We previously found that intermittent hyperbaric oxygen exposure increases metabolic enzyme activity in soleus muscle. Since the metabolic enzyme activities of the heart and diaphragm of healthy animals are difficult to alter, we questioned whether intermittent hyperbaric oxygenation would provide a stimulus sufficient to increase metabolic enzyme activity. Therefore, we exposed 36 rabbits (4 groups of 9) twice daily for 90 min 5 days/wk to either 100% O2 at 243 kPa, 8.5% O2, and 91.5% N2 at 243 kPa, 100% O2 at 101 kPa, or 21% O2 at 101 kPa. After 4 wk of treatment, the activities of citrate synthase, succinate dehydrogenase, alpha-glycerophosphate dehydrogenase, phosphofructokinase, and glyceraldehyde-3-phosphate dehydrogenase were measured. In both the heart and the diaphragm, none of the treatments significantly altered the mean enzyme activities for any of the enzymes measured. Therefore, it seems that the hyperbaric oxygenation treatment protocols used do not induce an increase in metabolic enzyme activity in the heart and diaphragm in healthy animals.
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