Stroma, Stroma Everywhere (Far More Than You Think)

Abstract Pancreatic ductal adenocarcinomas with high stromal content are shown to have greatly reduced overall survival, consistent with previous reports that stroma may limit drug delivery. In contrast to expectations, metastatic lesions were found to harbor as much stroma as primary tumors. Clin Cancer Res; 21(15); 3366–8. ©2015 AACR. See related article by Whatcott et al., p. 3561