Estimating Average Causal Effects Under Interference Between Units

This paper presents a randomization-based framework for estimating causal effects under interference between units. The framework integrates three components: (i) an experimental design that defines the probability distribution of treatment assignments, (ii) a mapping that relates experimental treatment assignments to exposures received by units in the experiment, and (iii) estimands that make use of the experiment to answer questions of substantive interest. Using this framework, we develop the case of estimating average unit-level causal effects from a randomized experiment with interference of arbitrary but known form. The resulting estimators are based on inverse probability weighting. We provide randomization-based variance estimators that account for the complex clustering that can occur when interference is present. We also establish consistency and asymptotic normality under local dependence assumptions. We discuss refinements including covariate-adjusted effect estimators and ratio estimation. We illustrate and assess empirical performance with a naturalistic simulation using network data from American high schools.