Nigragillin, Nigerazine B and Five Naphtho-γ;-pyrones from Aspergillus japonicus Isolated from Hot Desert Soil

Background: Microorganisms are highly diverse sources of bioactive natural products. A valuable set of fungi has been encountered in the hot Egyptian desert soils. The aims of this paper were to isolate soil thermophilic fungi and detect their bioactive metabolites. Keywords: Soil fungi, Aspergillus japonicus, piperazine, naphtho-γ-pyrone, natural products, secondary metabolites, antibacterial.