生物
坏死性下垂
癌症研究
交易激励
转录因子
细胞生物学
染色质重塑
程序性细胞死亡
细胞凋亡
基因
遗传学
作者
Han-Hee Park,Hwa-Ryeon Kim,Sangyeong Park,Sung‐Min Hwang,Sun Mi Hong,Sangwook Park,Ho Chul Kang,Michael J. Morgan,Jong‐Ho Cha,Dakeun Lee,Jae‐Seok Roe,You‐Sun Kim
出处
期刊:Molecular Cancer
[BioMed Central]
日期:2021-08-21
卷期号:20 (1): 107-107
被引量:157
标识
DOI:10.1186/s12943-021-01399-3
摘要
Our data suggest that RIPK3 activation-dependent derepression of TRIM28 in cancer cells leads to increased immunostimulatory cytokine production in the tumor microenvironment, which then contributes to robust cytotoxic anti-tumor immunity.
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