破骨细胞
医学
细胞生物学
生物
免疫学
癌症研究
神经科学
内科学
受体
作者
Guillaume Mabilleau,Hélène Libouban,Valérie Geoffroy
标识
DOI:10.1016/j.tem.2021.04.004
摘要
McDonald and colleagues reported osteoclast-related dynamic mechanisms that lead, by fission, to osteomorphs; motile, fusion-competent cells capable of forming bone-resorbing osteoclasts. scRNA-seq analyses revealed that osteomorphs are transcriptionally distinct from osteoclasts and macrophages and might be implicated in rare and common bone diseases in humans.
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