Self‐Assembly of One‐ and Two‐Dimensional Hemoprotein Systems by Polymerization through Heme–Heme Pocket Interactions

Abstract Supramolecular protein polymers : When a heme moiety was introduced to the surface of an apo‐cytochrome b 562 (H63C) mutant, supramolecular polymers formed through noncovalent heme–heme pocket interactions. The incorporation of a heme triad as a pivot molecule in the protein polymer further led to a two‐dimensional protein network structure, which was visualized by tapping‐mode atomic force microscopy (see picture). magnified image