Meningococcal vaccination and chronic kidney disease

Meningococcal vaccination and chronic kidney diseaseSir, We read with great interest the editorial review about vaccination and chronic kidney disease by Janus et al [1].Although this article is focused on end-stage renal disease patients, we think that it is possible to mention the meningococcal vaccine.This immunization is usually recommended for people exposed to a case of severe meningococcal infection, or for people travelling in endemic zones (sub-Saharan meningitis belt) in close contact with the local population.In some countries, this vaccine is incorporated in national vaccination programmes [2].A few years ago, a risk of relapse of nephrotic syndrome was signalled, after meningococcal C conjugate vaccine [3].However, that has been invalidated by a more recent study where no link was found between vaccination and a risk of relapse [4].Thus the use of this vaccine, when necessary, can be recommended.However, there is a lack of data upon the degree of the immune response to this kind of vaccine in immunosuppressed patients.For asplenic individuals, for example, a double dose of vaccine has been proposed [5].