Highly Selective Catalytic Friedel – Crafts Acylation of Activated Aromatic Compounds Using the I2.DMF Complex as Catalyst

A novel method has been developped for synthesizing aryl ketones by means of I2-DMF mediated Friedel – Crafts acylation of aromatic substrates. The reaction is applicable to activated aromatic compounds. The present process is carried out under conditions involving minimal wastes and energy-consumption as compared to the use of molecular iodine. Keywords: I2-DMF, AlCI3-DMF, anisole, aromatic substrates, heteroaromatic substrates, Friedel-Crafts reaction