Rational design of cationic cyclooligosaccharides as efficient gene delivery systems
作者
Alejandro Díaz‐Moscoso,Patricia Balbuena,Marta Gómez-Garcı́a,Carmen Ortiz Mellet,Juan M. Benito,Loïc Le Gourriérec,Christophe Di Giorgio,Pierre Vierling,Antonino Mazzaglia,Norberto Micali,Jacques Defaye,José M. Garcı́a Fernández
出处
期刊:Chemical Communications [Royal Society of Chemistry] 日期:2008-01-01卷期号: (17): 2001-2001被引量:82
Self-assembled cyclodextrin (CD)-DNA nanoparticles (CDplexes) exhibiting transfection efficiencies significantly higher than PEI-based polyplexes have been prepared from homogeneous seven-fold symmetric polyaminothiourea amphiphiles constructed on a beta-cyclodextrin scaffold.