Straightforward α-allylation of carbonyl compounds with alkenes via α-carbonyl radical intermediates
化学
药物化学
有机化学
作者
Sien Liu,Yanjing Liao,Hongyi Li,Biping Xu,Zhang Xiao-feng,Yaping Shang,Weiping Su
出处
期刊:Organic chemistry frontiers [The Royal Society of Chemistry] 日期:2024-01-01
标识
DOI:10.1039/d3qo02045b
摘要
We report that the direct oxidative cross-coupling of carbonyl compounds with simple alkenes is realized to synthesize α-allylated carbonyl compounds by identifying the bisphosphine ligand BINAP that enables the copper catalyst to integrate two different catalytic cycles in a one-pot system.