自愈水凝胶
组织工程
材料科学
生物医学工程
纳米技术
高分子化学
工程类
作者
Juan Yang,Qingyuan Tan,Ka Li,Jinfeng Liao,Ying Hao,Y.M. Chen
出处
期刊:ACS Biomaterials Science & Engineering
[American Chemical Society]
日期:2024-03-08
标识
DOI:10.1021/acsbiomaterials.3c01485
摘要
The development of static hydrogels as an optimal choice for bone tissue engineering (BTE) remains a difficult challenge primarily due to the intricate nature of bone healing processes, continuous physiological functions, and pathological changes. Hence, there is an urgent need to exploit smart hydrogels with programmable properties that can effectively enhance bone regeneration. Increasing evidence suggests that photoresponsive hydrogels are promising bioscaffolds for BTE due to their advantages such as controlled drug release, cell fate modulation, and the photothermal effect. Here, we review the current advances in photoresponsive hydrogels. The mechanism of photoresponsiveness and its advanced applications in bone repair are also elucidated. Future research would focus on the development of more efficient, safer, and smarter photoresponsive hydrogels for BTE. This review is aimed at offering comprehensive guidance on the trends of photoresponsive hydrogels and shedding light on their potential clinical application in BTE.
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